It is the 1960s. Kristen (Amber Heard), a beautiful but troubled young woman, finds herself held against her will in a remote ward of a psychiatric hospital. Disoriented, she has no idea why she has been brought to this place and no memory of her life before she was admitted - all she knows is that she isn't safe. As the other patients begin to disappear one-by-one, Kristen must find a way out of this hellish place before she too becomes a victim. In her struggle to escape, she will uncover a truth far more dangerous and horrifying than anyone could have imagined.